Protein name:
Metalloproteinase inhibitor 2 ;
Alternative:
Tissue inhibitor of metalloproteinases 2 (TIMP-2) ;
Organism:
Dog (Canis familiarisCanis lupus familiaris).
General Annotation
Sub Unit:
Interacts (via the C-terminal) with MMP2 (via the C-terminal PEX domain); the interaction inhibits the MMP2 activity.
Function:
Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor.
Subcellular Location:
Secreted
Protein Attributes:
50:
MGAAARSLRL | ALGLLLLATL | PRPADACSCS | PVHPQQAFCN | ADVVIRAKAV |
100:
SVKEVDSGND | IYGNPIKRIQ | YEIKQIKMFK | GPDKDIEFIY | TAPSSAVCGV |
150:
SLDIGGKKEY | LIAGKAEGNG | KMHITLCDFI | VPWDTLSSTQ | KKSLNHRYQM |
200:
GCECKITRCP | MIPCYISSPD | ECLWMDWVTE | KSINGHQAKF | FACIKRSDGS |
220:
CAWYRGAAPP | KQEFLDIEDP |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Rat
Mouse
Chicken
Dog
Bovine
Rabbit
ELISA Kit for Dog Metalloproteinase inhibitor 2
ELISA Kit for Dog Metalloproteinase inhibitor 2
ELISA Kit for Dog Metalloproteinase inhibitor 2
ELISA Kit for Dog Metalloproteinase inhibitor 2
ELISA Kit for Dog Metalloproteinase inhibitor 2
ELISA Kit for Dog Metalloproteinase inhibitor 2
ELISA Kit for Dog Metalloproteinase inhibitor 2
CLIA Kit for Dog Metalloproteinase inhibitor 2
CLIA Kit for Dog Metalloproteinase inhibitor 2
CLIA Kit for Dog Metalloproteinase inhibitor 2
CLIA Kit for Dog Metalloproteinase inhibitor 2
CLIA Kit for Dog Metalloproteinase inhibitor 2
CLIA Kit for Dog Metalloproteinase inhibitor 2
CLIA Kit for Dog Metalloproteinase inhibitor 2
Polyclonal Antibody for Dog Metalloproteinase inhibitor 2
Polyclonal Antibody for Dog Metalloproteinase inhibitor 2
Polyclonal Antibody for Dog Metalloproteinase inhibitor 2
Polyclonal Antibody for Dog Metalloproteinase inhibitor 2
Polyclonal Antibody for Dog Metalloproteinase inhibitor 2
Polyclonal Antibody for Dog Metalloproteinase inhibitor 2
Polyclonal Antibody for Dog Metalloproteinase inhibitor 2
Monoclonal Antibody for Dog Metalloproteinase inhibitor 2
Monoclonal Antibody for Dog Metalloproteinase inhibitor 2
Monoclonal Antibody for Dog Metalloproteinase inhibitor 2
Monoclonal Antibody for Dog Metalloproteinase inhibitor 2
Monoclonal Antibody for Dog Metalloproteinase inhibitor 2
Monoclonal Antibody for Dog Metalloproteinase inhibitor 2
Monoclonal Antibody for Dog Metalloproteinase inhibitor 2
Protein for Dog Metalloproteinase inhibitor 2
Protein for Dog Metalloproteinase inhibitor 2
Protein for Dog Metalloproteinase inhibitor 2
Protein for Dog Metalloproteinase inhibitor 2
Protein for Dog Metalloproteinase inhibitor 2
Protein for Dog Metalloproteinase inhibitor 2
Protein for Dog Metalloproteinase inhibitor 2
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
2.
"Molecular studies of tissue inhibitors of metalloproteinases (TIMPs) in canine joints."
Carter S.D.
,
Barnes A.
,
Clegg P.D.
Submitted (1998-09) to the EMBL/GenBank/DDBJ databases
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] OF 48-138
3.
"Canine tissue inhibitor of matrix metalloproteinase-2 (TIMP-2)."
Balkin R.
,
Fang Y.
,
Kitchell B.
Submitted (1999-09) to the EMBL/GenBank/DDBJ databases
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] OF 69-220
tissue :
Fibrosarcoma .